Test Category: Immunology
Investigation Name:Haemophilus influenza type B IgG antibody
Alias or Abbreviation:HIB, FAB, Functional antibodies
Accreditation:Yes
Intro:
Indication:Immunodeficiency
Further information:
Functional antibodies should only be requested if there is a clinical suspicion of antibody deficiency (primary or secondary).
The recommended first line Immunology tests are:-
• Immunoglobulin levels (IgG, IgA and IgM)
• Electrophoresis
The second line testing, which includes functional antibodies, should only be requested if:-
• There is a strong clinical history of recurrent or persistent infection
• At least 2 Immunoglobulin isotypes are lower than reference limits
• To assess immune response to vaccines (pre- and post-vaccine)
Pathology Laboratory:Immunology Laboratory
Requestable Seperately?Yes
Minimum Sample Volume:0.5mL
Expected Turnaround Time:7 days
Test Code:HIB
Sample Type:
Serum Gel Tube (Gold top)Complex Reference Range:0.15 mg/L = Minimum
protective level
1.0 mg/L= Optimum
protective level
Collection Conditions / Other Information:
Referred to Another Laboratory?No
Storage Requirements:Refrigerate (2 – 8C) after serum separation
Posting Address / Requirements:Ambient temperature, First Class Post
NPEX / PDF Reporting Available:Yes
EQA Scheme:Yes
Further information:Functional antibodies should only be requested if there is a clinical suspicion of antibody deficiency (primary or secondary) and as a second line test.
Lead Contact Details:rwh-tr.bcpsimmunologyclinicalqueries@nhs.net
Email Address For Chasing Results:rwh-tr.ImmunologyLab@nhs.net
Methodology:ELISA
UKAS Reference Number:9580
Site Sample Tested:Immunology, New Cross Hospital, Wolverhampton
Minimum Request Interval (MRI):180 days (6 months) over 16y only
Contact Number:01902 695 279 or Ext 85279
