Test Category: Immunology
Investigation Name:Liver-kidney microsomal antibodies (LKM) [Liver antibodies]
Alias or Abbreviation:LKM, Liver antibody
Intro:
Indication: Autoimmune Hepatitis (AIH) Further information: Anti LKM antibodies are associated with type two autoimmune hepatitis (AIH) and in some patients they are associated with hepatitis C infection. LKM antibodies are found only in a small number of patients with autoimmune chronic active hepatitis and drug-induced hepatitis, but are highly specific. Forms part of the Liver Auto-immune profile which includes tests for: • Mitochondrial antibody (AMA) • Smooth muscle antibody (SMA) • Liver- kidney microsomal antibody (LKM) • Gastric Parietal antibody (GPC)Requestable Seperately?No
Minimum Sample Volume:1mL
Test Code:LKS
Sample Type:
Serum Gel Tube (Gold top)Complex Reference Range:Positive/ Negative
Collection Conditions / Other Information:1st class post or Transport
Referred to Another Laboratory?No
Storage Requirements:Ambient temperature
NPEX / PDF Reporting Available:Yes
EQA Scheme:Yes
Further information:Available as part of the Liver Auto-immune profile only (LKS)
Lead Contact Details:rwh-tr.bcpsimmunologyclinicalqueries@nhs.net
Email Address For Chasing Results:rwh-tr.ImmunologyLab@nhs.net
Methodology:Indirect Immunofluorescence
UKAS Reference Number:Awaiting assessment
Site Sample Tested:Immunology, New Cross Hospital, Wolverhampton
Minimum Request Interval (MRI):180 days (6 months) over 16y only
