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Test Category: Specialist BiochemistryToxicology

Investigation Name:Quetiapine

Alias or Abbreviation:QUET/QUE

Accreditation:UKAS Accredited ISO15189:2022, on scope

Intro:

Quetiapine is an atypical antipsychotic used in the management of schizophrenia, bipolar disorder, and major depressive disorder. While routine therapeutic drug monitoring is not standard practice, measurement may can be beneficial in suspected non-compliance, or in patients with an inadequate therapeutic response or unexpected side effects, such as excessive sedation, hypotension, or metabolic disturbances, which could suggest subtherapeutic or toxic drug levels.

Pathology Laboratory:Toxicology Laboratory

Requestable Seperately?Yes

Units:µg/L

Minimum Sample Volume:1mL plasma or serum.

Expected Turnaround Time:7 working days

Test Code:QUE

Sample Type:

Minimum of 1mL of EDTA plasma or serum.
Please note: Gel tubes can NOT be used for this assay.

Complex Reference Range:Maximum drug efficacy 50-200 µg/L
Trough specimen taken pre dose or minimum 12 hrs post dose

Referred to Another Laboratory?No

Storage Requirements:Send at ambient temperature in normal postal system and store at 4°C prior to sending.

Posting Address / Requirements:Sandwell Health Campus
Specialist Chemistry
Pathology Department
Lyndon B71 4HJ

NPEX / PDF Reporting Available:NPEX and PDF reporting available.

EQA Scheme:LCG Toxicology TDM Scheme.

Further information:Samples should be collected immediately before the next dose, i.e. pre-dose (trough), or a minimum 12 hours post-dose.
Therapeutic ranges only apply to pre-dose (trough) samples.

Lead Contact Details:Hayley Sharrod-Cole, Consultant Clinical Scientist
Email: hayley.sharrod-cole@nhs.net

Email Address For Chasing Results:rwh-tr.bcpsspecialistchemistryenquiries@nhs.net

Methodology:UPLC-MS/MS

Site Sample Tested:City Health Campus

Cost:Please email: bcpspathology.info@nhs.net for further details

Contact Number:0121 507 4138