Investigation Name:Renin

Alias or Abbreviation:PRA or Plasma Renin Activity

Accreditation:UKAS Accredited ISO15189:2022, currently ETS due to equipment refresh (updated November 2025)

Pathology Laboratory:Clinical Chemistry/ Biochemistry

Requestable Seperately?Yes

Units:mIU/L

Minimum Sample Volume:1 mL

Expected Turnaround Time:7 working days from receipt

Test Code:REN (If renin only requested) ALRE (If renin & aldosterone requested)

Sample Type:

Complex Reference Range:Upright: 5.3 - 99.1 mIU/L Supine: 4.2 - 59.7 mIU/L
Aldosterone:Renin Ratio <31 makes primary hyperaldosteronism (Conn's syndrome) unlikely
Aldosterone:Renin Ratio >=31 makes primary hyperaldosteronism (Conn's syndrome) more likely
For advice contact Duty Biochemist Ext: 5290

Collection Conditions / Other Information:LAB INSTRUCTIONS: Sample should be separated and frozen within 8 hours of collection. Do not chill sample collection tubes or store collection tubes on ice. 4 freeze thaw cycles acceptable
Separate immediately into aliquot tube, and store frozen plasma at -20°C. Transport frozen.

Referred to Another Laboratory?No

Storage Requirements:Store plasma frozen

Posting Address / Requirements:Send frozen courier
Sandwell Health Campus
Specialist Chemistry
Pathology Department
Lyndon, B71 4HJ

NPEX / PDF Reporting Available:Yes

EQA Scheme:UKNEQAS Steroids scheme

Methodology:IDS-iSYS

Site Sample Tested:Manuals Laboratory, Sandwell Health Campus

Cost:Please email: bcpspathology.info@nhs.net for further details

Contact Number:0121 507 5162