C1 Esterase Inhibitor (functional) - Black Country Pathology Services

Investigation Name:C1 Esterase Inhibitor (functional)

Alias or Abbreviation:C1INH, Functional complement

Intro:

Indication: Hereditary Angioedema
Further information:
Most cases have reduced serum C1Inh levels. In 10% of cases there are normal or elevated levels of C1Inh but this is functionally inactive. In hereditary angioedema C4 levels are almost always reduced and C1q levels are normal.
In acquired angioedema (associated with B cell neoplasia) C1Inh is reduced and both C4 and C1q are also usually reduced.

Pathology Laboratory:Immunology Laboratory

Requestable Seperately?Yes

Part of Profile:No

Minimum Sample Volume:0.5mL

Expected Turnaround Time:21 Working days

Test Code:C1FA

Sample Type:

Sodium Citrate (blue top)

Complex Reference Range:Normal = 70 –130%

Reference Laboratory Details:Immunology Dept,Medical School, Edgbaston, Birmingham, B15 2TT

Referred to Another Laboratory?Yes

Reference Lab Code:BMMI

Storage Requirements:Ambient temperature

Posting Address / Requirements:Urgent transport - Must be received in the laboratory within 1 hour of collection

Further information:Laboratory use only: Plasma should be separated within the hour, frozen and sent to the referral laboratory to arrive frozen.

Lead Contact Details:Clinical Queries Email: rwh-tr.bcpsimmunologyclinicalqueries@nhs.net

Email Address For Chasing Results:rwh-tr.ImmunologyLab@nhs.net

Contact Number:01902 695 279 or Ext 85279