Test Category: Immunology
Investigation Name:Anti-Pneumococcal Capsular Polysaccharide (PCP) antibody
Alias or Abbreviation:Pneumoccocal, FAB, Functional antibodies
Intro:
Indication: Immunodeficiency Further information: Functional antibodies should only be requested if there is a clinical suspicion of antibody deficiency (primary or secondary). The recommended first line Immunology tests are:- • Immunoglobulin levels (IgG, IgA and IgM) • Electrophoresis The second line testing, which includes functional antibodies, should only be requested if:- • There is a strong clinical history of recurrent or persistent infection • At least 2 Immunoglobulin isotypes are lower than reference limits • To assess immune response to vaccines (pre- and post-vaccine) Please note that whole cell pneumococcal assays may not provide accurate information in children who have previously received Prevenar13 vaccination.Requestable Seperately?Yes
Minimum Sample Volume:0.5mL
Test Code:PNEU
Sample Type:
Serum Gel Tube (Gold top)Complex Reference Range:>30 mg/L = Normal adult level
Collection Conditions / Other Information:1st class post or Transport
Referred to Another Laboratory?No
Storage Requirements:Ambient temperature
NPEX / PDF Reporting Available:Yes
EQA Scheme:Yes
Further information:Functional antibodies should only be requested if there is a clinical suspicion of antibody deficiency (primary or secondary) and as a second line test.
Lead Contact Details:rwh-tr.bcpsimmunologyclinicalqueries@nhs.net
Email Address For Chasing Results:rwh-tr.ImmunologyLab@nhs.net
Methodology:ELISA
UKAS Reference Number:9580
Site Sample Tested:Immunology, New Cross Hospital, Wolverhampton
