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Test Category: Immunology

Investigation Name:Aquaporin 4 (AQP4) Antibodies (CSF)

Alias or Abbreviation:AQP4, NMO

Accreditation:Not on UKAS 9556 scope

Intro:

Indication:
Neuromyelitis optica or Devic’s disease

Further information:
Aquaporin 4 (AQP4) is the major autoantigen in neuromyelitis optica (NMO or Devic's disease).
Antibodies to AQP4 are found in >80% of NMO patients and around 50% of patients with longitudinally extensive transverse myelitis. They are infrequent in patients with optic neuritis without spinal cord involvement.

Pathology Laboratory:Immunology Laboratory

Requestable Seperately?Yes

Minimum Sample Volume:1mL

Expected Turnaround Time:21 working days

Test Code:AQUS

Sample Type:

CSF

Complex Reference Range:Positive/Negative

Reference Laboratory Details:Clinical Immunology Service, University of Birmingham

Referred to Another Laboratory?Yes

Storage Requirements:Refrigerate (2 – 8C)

Posting Address / Requirements:First Class post at ambient temperature

Lead Contact Details:rwh-tr.bcpsimmunologyclinicalqueries@nhs.net

Email Address For Chasing Results:rwh-tr.ImmunologyLab@nhs.net

Contact Number:01902 695 279 or Ext 85279