Test Category: Immunology
Investigation Name:Aquaporin 4 (AQP4) Antibodies (Serum)

Alias or Abbreviation:AQP4, NMO
Intro:
Indication:Neuromyelitis optica or Devic’s disease.
Further information:
Aquaporin 4 (AQP4) is the major autoantigen in neuromyelitis optica (NMO or Devic's disease). Antibodies to AQP4 are found in >80% of NMO patients and around 50% of patients with longitudinally extensive transverse myelitis. They are infrequent in patients with optic neuritis without spinal cord involvement.
Pathology Laboratory:Immunology Laboratory
Requestable Seperately?Yes
Minimum Sample Volume:1 mL
Expected Turnaround Time:21 working days
Test Code:AQUS
Sample Type:
Serum Gel Tube (Gold top)Complex Reference Range:Positive/ Negative
Reference Laboratory Details:Immunology Department, Medical School, Birmingham
Referred to Another Laboratory?Yes
Storage Requirements:Refrigerate (2 – 8C) after serum separation
Posting Address / Requirements:First Class post at ambient temperature
Lead Contact Details:rwh-tr.bcpsimmunologyclinicalqueries@nhs.net
Email Address For Chasing Results:rwh-tr.ImmunologyLab@nhs.net
Contact Number:01902 695 279 or Ext 85279

