Test Category: Specialist Biochemistry
Investigation Name:Barium- Blood

Alias or Abbreviation:Ba
Accreditation:UKAS ISO15189:2022 Accredited test: On scope
Intro:
Barium is a non-essential element, used in the production of fluorescent lamps, fireworks, paint, glass, rubber, bricks and drilling fluid also known as “drilling mud”.Insoluble barium sulphate is used medically as a diagnostic radio-opaque contrast medium during x-rays. Serious toxicity characterised by stomach irritation, cardiac arrhythmias, tremors, muscle weakness and paralysis may arise following the ingestion of soluble barium salts. Barium is thought to block potassium ion channels leading to persistent hypokalaemia.
Occupational exposure may occur by inhalation of dust arising from barium ores. Accumulation of the dust in the lungs may manifest as baritosis, a benign pneumoconiosis.
Measurement of barium in blood, plasma or serum appears to be the most appropriate approach in investigating acute exposure. Occupational exposure is typically monitored by urine analysis.
Pathology Laboratory:Trace Metals Laboratory
Requestable Seperately?Yes
Units:nmol/L
Minimum Sample Volume:500 µL whole blood
Expected Turnaround Time:14 working days.
Urgent analysis where clinically indicated may be arranged directly with the laboratory.
Test Code:BA
Sample Type:
Preferred: Trace element free EDTA or sodium heparin whole bloodAccepted: EDTA whole blood if contamination testing has confirmed that the tube lot being used is barium-free.
Complex Reference Range:Less than 10 nmol/L
Referred to Another Laboratory?No
Storage Requirements:Store at 4 °C prior to dispatch
Posting Address / Requirements:Ambient temperature, 1st class post.
Sandwell Health Campus,
Specialist Chemistry,
Pathology Department,
Lyndon,
B71 4HJ
NPEX / PDF Reporting Available:Yes
EQA Scheme: QUEBEC Multielement External Quality Assessment Scheme (QMEQAS)
Further information:We are a designated Supra-Regional Assay Service (SAS) Laboratory for Trace Elements.
Lead Contact Details:Dr Nicola Barlow, Consultant Clinical Scientist,
SAS Director Trace Elements Laboratory
Email: nicola.barlow1@nhs.net
Email Address For Chasing Results:rwh-tr.bcpsspecialistchemistryenquiries@nhs.net
Methodology:Inductively coupled plasma mass spectrometry
Site Sample Tested:Sandwell Health Campus
Cost:Please email: bcpspathology.info@nhs.net for further details
Contact Number:Tel: 0121 507 5162