Test Category: Immunology
Investigation Name:Basal Ganglia Antibodies

Alias or Abbreviation:Basal ganglia, ABGA
Intro:
Indication: Sydenham’s chorea and PANDASFurther information:
Contains antibodies to:
• Enolase
• pyruvate kinase
• aldolase
Anti-basal ganglia antibodies (ABGA) have been found with extrapyramidal movement disorders of the basal ganglia and deep grey matter with post-rheumatic fever chorea (90% sensitivity) and tics being the common manifestations, although dystonia and myoclonus have also been reported in rare incidences.
Pathology Laboratory:Immunology Laboratory
Requestable Seperately?Yes
Minimum Sample Volume:0.5mL
Expected Turnaround Time:21 working days
Test Code:BGA
Sample Type:
Serum Gel Tube (Gold top)Complex Reference Range:Results as per reports
Collection Conditions / Other Information:Haemolysed samples are unsuitable for analysis
Reference Laboratory Details:Institute of Neurology, Queen’s Square, London
Referred to Another Laboratory?Yes
Storage Requirements:Ambient temperature
Posting Address / Requirements:1st class post/ Trust transport
Lead Contact Details:Clinical Queries Email: rwh-tr.bcpsimmunologyclinicalqueries@nhs.net
Email Address For Chasing Results:rwh-tr.ImmunologyLab@nhs.net
Site Sample Tested:Immunology, New Cross Hospital, Wolverhampton
Contact Number:01902695279