Test Category: Immunology
Investigation Name:C1Q Antibodies
Alias or Abbreviation:C1Q abs
Intro:
Indication:Hypocomplementaemic Urticarial Vasculitis (HUV), Systemic Lupus Erythematosus (SLE) and Lupus Nephritis.
Further information:
Anti-C1q antibodies are used in the diagnosis of HUV. They are also found in patients with SLE and in particular are markers of renal involvement in SLE. Patients without C1q autoantibodies have a very low risk of developing an active lupus nephritis.
In contrast, high titres of C1q autoantibodies indicate a high risk in developing an active lupus nephritis, particularly if they have previously suffered from lupus nephritis.
Pathology Laboratory:Immunology Laboratory
Requestable Seperately?Yes
Minimum Sample Volume:2ml
Expected Turnaround Time:3 weeks
Test Code:C1QA
Sample Type:
Serum Gel Tube (Gold top)Complex Reference Range:"Negative = < 15 U/mL Positive = > 15 U/mL"
Reference Laboratory Details:Immunology, Sheffield
Referred to Another Laboratory?Yes
Storage Requirements:Ambient temperature
Lead Contact Details:Clinical queries email: rwh-tr.bcpsimmunologyclinicalqueries@nhs.net
Email Address For Chasing Results:rwh-tr.ImmunologyLab@nhs.net
Site Sample Tested:Immunology, New Cross Hospital, Wolverhampton
Contact Number:01902 695279
