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Test Category: Biochemistry

Investigation Name:Cognitive biomarker/Alzheimer’s disease biomarker/Dementia biomarker

Alias or Abbreviation:TAU 217

Pathology Laboratory:Clinical Chemistry/ Biochemistry

Requestable Seperately?No

Minimum Sample Volume:500µL spun EDTA plasma and aliquoted in each of two 2 mL tubes

Expected Turnaround Time:15 Working days

Test Code:AOT

Sample Type:

• Plasma sample must be collected into Plasma EDTA Tube 4-8 mls
• Sample must be received by the laboratory within 4 hours of collection
• Sample must not be haemolysed .

Collection Conditions / Other Information:Sample volume in each tube should be minimum 500ul and make at least 3 aliquots per patient.
Lab Instructions: 2 x aliquots need to be sent to UCL, 1 to be kept on-site

Reference Laboratory Details:Neuroimmunology & CSF Laboratory, (Box 76) 9th floor UCL Queen Square Institute of Neurology Queen Square London WC1N 3BG
General result enquiries: uclh.enquiry.nhnn-nicl@nhs.net
Telephone: 020 3448 3812
Lab Instructions: ALL couriers must report to ground floor reception UCL Queen Square Institute of Neurology. Couriers please note: the department is within the UCL Queen Square Institute of Neurology building (also known as Queen Square House on some maps). It is adjacent to the National Hospital for Neurology and Neurosurgery but is a separate building - a large grey tower block.

Referred to Another Laboratory?Yes

Storage Requirements:• For long-term pre-analytical storage, plasma must be kept frozen at -80C
•

Further information:Results may be artificially low if samples are not processed correctly. Renal function should be tested.

Lead Contact Details:Pathology Reception: 01902 307999 - Ext 88266
Sue Onion (RWT Reception Manager), Email: susan.onions@nhs.net (01902 307999)
UCLH General Result Enquiries,
Email: uclh.enquiry.nhnn-nicl@nhs.net , Tel: 020 3448 3812
Clinical advice :
RWT - Dr Scotton - Email: williamscotton@nhs.net
SWBH - Dr Duncan Street - Email: duncan.street@nhs.net , 07483191216 (Trust mobile)

Methodology:Chemiluminescent enzyme immunoassay (CLEIA)