Investigation Name:Cryoglobulin

Alias or Abbreviation:CRYO

Accreditation:UKAS ISO15189:2022 Accredited test: On scope

Pathology Laboratory:Proteins laboratory

Requestable Seperately?No

Minimum Sample Volume:2.5 mls

Expected Turnaround Time:7 days

Test Code:CRYG

Sample Type:

Maximum Add on Time:N/A

Complex Reference Range:Normal range: negative
Abnormal results:
 Type 1 - Monoclonal Immunoglobulin (usually IgM) associated with malignant disease.
 Type 2 – Mixed cryoglobulins usually with rheumatoid factor activity found in some LPDs but are generally found to be idiopathic.
 Type 3 – Mixed cryoglobulins consisting of immune complexes (polyclonal). Associated with “aberrant immunity” eg SLE, RA, infection (particularly Hep C).
 Cryofibrinogen present. Cryofibrinogenaemia is a disorder that occurs without any other health concerns (rare), or secondary to various disorders, including: specific cancers (such as Non-Hodgkin lymphoma and colorectal cancer), autoimmune diseases, malignancies, and infections

Collection Conditions / Other Information:IMPORTANT, collection conditions are vital to accurate analysis.
Patient should attend main OPD or Phlebotomy where all pre-warmed collection equipment (at 37°C) is available.
Prior to sample collection, please contact the laboratory on extension: 82710 for New Cross hospital.

Referred to Another Laboratory?No

Site Sample Tested:Hub laboratory RWT

Contact Number:01902 307999 ext 88266