Cyclic Citrullinated Peptide IgG antibody (CCP) - Black Country Pathology Services

Investigation Name:Cyclic Citrullinated Peptide IgG antibody (CCP)

Alias or Abbreviation:CCP, ACPA

Accreditation:Yes

Intro:

Indication:
Rheumatoid arthritis

Further information:
CCP antibodies have been shown to be highly specific for RA and appear early in the disease process when diagnosis is most difficult and intervention most effective. CCP antibody measurement is of value in confirming the diagnosis of RA in patients with atypical presentation, excluding a diagnosis of RA in patients where the RF is positive but the clinical features are equivocal and also as an indicator of early RA.

Pathology Laboratory:Immunology laboratory

Requestable Seperately?Yes

Minimum Sample Volume:1mL

Expected Turnaround Time:4 days

Test Code:CCP

Sample Type:

Serum Gel Tube (Gold top)/ Plasma

Complex Reference Range:<7 U/mL = Negative

Referred to Another Laboratory?No

Storage Requirements: Refrigerate (2 – 8C) after serum separation

Posting Address / Requirements:Ambient temperature, First Class Post

NPEX / PDF Reporting Available:Yes

EQA Scheme:Yes

Lead Contact Details:rwh-tr.bcpsimmunologyclinicalqueries@nhs.net

Email Address For Chasing Results:rwh-tr.ImmunologyLab@nhs.net

Methodology:Fluoroenzymeimmunoassay

UKAS Reference Number:9580

Site Sample Tested:Immunology, New Cross Hospital, Wolverhampton

Minimum Request Interval (MRI):180 days (6 months) over 16y only

Contact Number:01902 695279 or Ext 85279