Cyclic Citrullinated peptide IgG antibody (CCP) - Black Country Pathology Services

Investigation Name:Cyclic Citrullinated peptide IgG antibody (CCP)

Alias or Abbreviation:CCP, ACPA

Intro:

Indication: Rheumatoid arthritis Further information: CCP antibodies have been shown to be highly specific for RA and appear early in the disease process when diagnosis is most difficult and intervention most effective. CCP antibody measurement is of value in confirming the diagnosis of RA in patients with atypical presentation, excluding a diagnosis of RA in patients where the RF is positive but the clinical features are equivocal and also as an indicator of early RA.

Requestable Seperately?Yes

Minimum Sample Volume:1mL

Test Code:CCP

Sample Type:

Serum Gel Tube (Gold top)/ Plasma

Complex Reference Range:<7 U/mL = Negative

Collection Conditions / Other Information:1st class post or Transport

Referred to Another Laboratory?No

Storage Requirements:Ambient temperature

NPEX / PDF Reporting Available:Yes

EQA Scheme:Yes

Lead Contact Details:rwh-tr.bcpsimmunologyclinicalqueries@nhs.net

Email Address For Chasing Results:rwh-tr.ImmunologyLab@nhs.net

Methodology:Fluoroenzymeimmunoassay

UKAS Reference Number:9580 (recommended)

Site Sample Tested:Immunology, New Cross Hospital, Wolverhampton

Minimum Request Interval (MRI):180 days (6 months) over 16y only