Investigation Name:Factor Xa (HEPA)

Alias or Abbreviation:Fxa, Heparin Assay, NOAC, DOAC,

Pathology Laboratory:Haematology Ext 88245

Requestable Seperately?No

Minimum Sample Volume:filled to line

Expected Turnaround Time:<2 days

Sample Type:

Maximum Add on Time:4 hours

Complex Reference Range:Prophylactic range for LMWH 0.3-0.5 Therapeutic ranges: LMWH 0.5 – 0.9 IU/mL UFH 0.3 - 0.7 IU/mL Orgaran 0.5 – 0.8 IU/mL Rivaroxaban 184 – 419 ng/mL Peak level (3-4 hours post dose) 6-137 ng/mL Trough Level (7 hours post dose) Apixaban

Collection Conditions / Other Information:Full sample must be taken 4 hours post anticoagulant administration and tested within 4 hours. Please state which anticoagulant drug patient is on as different calibration curves are required to be used. Paediatric sample tubes are available from the laboratory for children and difficult to bleed patients. These tubes require 1ml of blood to be taken. Underfilled or overfilled samples will not be processed as the ratio of anticoagulant to blood in the tube will be incorrect. Clotted and grossly haemolysed samples cannot be processed. Haemolysis, Icterus and lipaemia may interfere with testing and so manual methods may be required to gain results.

Referred to Another Laboratory?No