Test Category:
Investigation Name:Ganglionic Acetylcholine Receptor Antibody
Alias or Abbreviation:Alpha3, AChR, α3AChR
Intro:
Indication:Autoimmune autonomic neuropathy.
Further information:
Ganglionic (alpha3) acetylcholine receptor antibodies have been reported in the sera of some patients with autoimmune autonomic neuropathy.
Their frequency is not yet known. They may also be found in patients with paraneoplastic disorders particularly in association with small cell lung carcinoma (SCLC) or thymoma.
Their presence suggests an immunotherapy-responsive condition.
Pathology Laboratory:Immunology Laboratory
Requestable Seperately?Yes
Minimum Sample Volume:1mL
Expected Turnaround Time:21 working days
Test Code:A3GA
Sample Type:
Serum Gel Tube (Gold top)Complex Reference Range:Negative = <10 pmol/L
Equivocal = 10 to <15 pmol/L
Positive = >=15 pmol/L
Reference Laboratory Details:Immunology, Oxford
Referred to Another Laboratory?Yes
Storage Requirements:Ambient temperature
Lead Contact Details:Clinical queries email: rwh-tr.bcpsimmunologyclinicalqueries@nhs.net
Email Address For Chasing Results:rwh-tr.ImmunologyLab@nhs.net
Site Sample Tested:Immunology, New Cross Hospital, Wolverhampton
Contact Number:01902 695279
