Test Category: Immunology
Investigation Name:Myelin Oligodendrocyte Glycoprotein Antibody (MOG)
Alias or Abbreviation:MOG
Accreditation:Not on UKAS 9556 scope
Intro:
Indication:ADEM or MS and more recently in patients with neuromyelitis Optica negative for AQP4 antibodies.
Further information:
MOG antibodies cause demyelination of the nerves leading to neurological symptoms that does not meet the typical criteria for Multiple Sclerosis. MOG antibody disease is similar in presentation to optic neuritis or transverse myelitis.
Patients presenting with symptoms of neuromyelitis optica but are seronegative for NMO antibodies may have MOG antibodies present. MOG antibodies can also be associated with Acute Disseminated Encephalomyelitis (ADEM) which is more common in children.
Pathology Laboratory:Immunology Laboratory
Requestable Seperately?Yes
Minimum Sample Volume:0.5mL Serum
Expected Turnaround Time:3 Weeks
Test Code:MOG
Sample Type:
Serum Gel Tube (Gold top)Complex Reference Range:Positive/ Negative
Reference Laboratory Details:Clinical Immunology Service, University of Birmingham
Referred to Another Laboratory?Yes
Storage Requirements:Refrigerate (2 – 8C) after serum separation
Posting Address / Requirements:First Class post at ambient temperature
Lead Contact Details:rwh-tr.bcpsimmunologyclinicalqueries@nhs.net
Email Address For Chasing Results:rwh-tr.ImmunologyLab@nhs.net
Contact Number:01902 695 279 or Ext 85279
