Test Category: Toxicology
Investigation Name:Olanzapines
Alias or Abbreviation:OLZ/ OLANZ
Intro:
Olanzapines are one of the most commonly prescribed atypical anti-psychotics for the treatment of schizophrenia. This assay is primarily used to monitor treatment/compliance. This is extracted from plasma/serum and analysed on UPLC-MS/MS.Pathology Laboratory:Toxicology, City Hospital
Requestable Seperately?No
Lower Reference Range Limit:N/A
Upper Reference Range Limit:N/A
Units: µg/L
Minimum Sample Volume:1mL
Expected Turnaround Time:5 working days from sample receipt.
Test Code:OLZ
Sample Type:
1mL of plasma or serum (into a gel-free tube e.g. K+EDTA). Please note: Gel tubes can NOT be used.Complex Reference Range:Maximum drug efficacy 20-40 µg/L Risk severe toxicity >100 µg/L Trough specimen taken pre dose or minimum 12 hrs post dose.
Referred to Another Laboratory?No
Storage Requirements:Send at ambient temperature in normal postal system and store at 4°C.
Posting Address / Requirements:Toxicology City Hospital Dudley Road Birmingham B18 7QH
NPEX / PDF Reporting Available:NPEX and PDF reporting available.
EQA Scheme:LGC Toxicology TDM Scheme.
Further information:Samples should be collected immediately before the next dose, i.e. pre-dose (trough), or a minimum 12 hours post-dose. Therapeutic ranges only apply to pre-dose (trough) samples. Contact the laboratory on : Tel: 0121 507 4138
Lead Contact Details:Dr Loretta Ford Toxicology Consultant Clinical Scientist 0121 507 6026
Email Address For Chasing Results:bcpspathology.info@nhs.net / swbh.toxicology@nhs.net
UKAS Reference Number:8407. Accredited to ISO 15189:2012
