Investigation Name:Primary Hyperoxaluria Metabolites – Urine

Pathology Laboratory:Clinical Chemistry/ Biochemistry

Requestable Seperately?No

Part of Profile:Yes

Tests in Profile:Glycolate; Glycerate; HOG and DHG

Minimum Sample Volume:5 mL needed for analysis

Expected Turnaround Time:7- 14 working days from receipt

Test Code:PHOM

Sample Type:

Complex Reference Range:Glycolate excretion 140-620 umol/24hr adults
Age related ranges for glycolate:creatinine ratio ,br/> Under 1 year 1-49 umol/mmol
1-4 years 2-54 umol/mmol
5-11 years 1-68 umol/mmol
>12 years 14-57 umol/mmol
Glycerate:creatinine ratio <100umol/mmol
4 hydroxy 2 oxoglutarate (HOG): creatinine ratio <11 umol/mmol
dihydroxyglutarate (DHG): creatinine ratio <40 umol/mmol

Collection Conditions / Other Information:For diagnosis and classification of primary hyperoxaluria in patients with unexplained hyperoxaluria.
Random urine acceptable - must acidify on receipt to pH 1

Reference Laboratory Details:Clinical Biochemistry, HSL Analytics LLP, 60 Whitfield Street, LONDON,W1T 4JF (Tel: 202 3447 2955)

Referred to Another Laboratory?Yes

Contact Number:01902 307 999 Ext 88266