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Test Category: Biochemistry

Investigation Name:Primary Hyperoxaluria Metabolites – Urine

Pathology Laboratory:Chemistry Referred Ext 85290

Requestable Seperately?No

Part of Profile:Profile

Tests in Profile:Glycolate;Glycerate;HOG and DHG

E-Requesting Tab:Other

Minimum Sample Volume:5mL needed for analysis

Expected Turnaround Time:7- 14 working days from receipt

Test Code:PHOM

Sample Type:

24hr urine acidified

Maximum Add on Time:N/A

Complex Reference Range:Glycolate excretion 140-620 umol/24hr adults Age related ranges for glycolate:creatinine ratio Under 1 year 1-49 umol/mmol 1-4 years 2-54 umol/mmol 5-11 years 1-68 umol/mmol >12 years 14-57 umol/mmol Glycerate:creatinine ratio <100umol/mmol 4 hydroxy 2 oxoglutarate (HOG): creatinine ratio <11 umol/mmol dihydroxyglutarate (DHG): creatinine ratio <40 umol/mmol

Collection Conditions / Other Information:For diagnosis and classification of primary hyperoxaluria in patients with unexplained hyperoxaluria Random urine acceptable - must acidify on receipt to pH 1

Reference Laboratory Details:Clinical Biochemistry, HSL Analytics LLP, 60 Whitfield Street, LONDON,W1T 4JF (Tel: 202 3447 2955)

Referred to Another Laboratory?Yes

Reference Lab Code:UCLC