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Test Category: Specialist BiochemistryToxicology

Investigation Name:Quetiapine

Alias or Abbreviation:QUET/QUE

Intro:

Quetiapine is an atypical anti-psychotic used for the treatment of schizophrenia, bipolar disorder and depression associated with bipolar disorder. It is often used to identify optimal treatment dosage and compliance. Quetiapine can also be used for recreational abuse/overdose which can be identified. This is analysed using UPLC-MS/MS.

Pathology Laboratory:Toxicology Lab

Requestable Seperately?Yes

Units:µg/L

Minimum Sample Volume:1mL plasma or serum.

Expected Turnaround Time:7 working days

Test Code:QUE

Sample Type:

Minimum of 1mL of plasma or serum (gel-free tube, e.g. K+EDTA). Please note: Gel tubes can NOT be used for this assay.

Complex Reference Range:Maximum drug efficacy 50-200 µg/L Trough specimen taken pre dose or minimum 12 hrs post dose

Referred to Another Laboratory?No

Storage Requirements:Send at ambient temperature in normal postal system and store at 4°C prior to sending.

Posting Address / Requirements:City Health Campus Toxicology Department Dudley Road Birmingham B18 7QH

NPEX / PDF Reporting Available:NPEX and PDF reporting available.NPEX and PDF reporting available.

EQA Scheme:LCG Toxicology TDM Scheme.

Further information:Samples should be collected immediately before the next dose, i.e. pre-dose (trough), or a minimum 12 hours post-dose. Therapeutic ranges only apply to pre-dose (trough) samples.

Lead Contact Details:Lauren Starbrook Consultant Clinical Scientist 0121 507 6026

Email Address For Chasing Results:rwh-tr.bcpsspecialistchemistryenquiries@nhs.net

UKAS Reference Number:8407. Accredited to ISO 15189:2012

Site Sample Tested:City Health Campus

Cost:Please email: bcpspathology.info@nhs.net for further details

Contact Number:0121 507 4138